HMB’s successor is called HICA

mistersalvo · **HMB’s successor is called HICA -** 03-07-2010, 01:03 PM

here are already supplements that contain HICA on the market, but they contain too little of the amino acid to be effective. Now everyone’s waiting for the product from Oy Elmomed, the company that the inventors of HICA set up; or someone who doesn’t take patent law so seriously and decides to market the leucine metabolite themselves. According to a human study published in the Journal of the International Society of Sports Nutrition, the substance is anabolic.

The compound we’re talking about is called L-leucic acid, but the Finns call it alpha-hydroxy-isocaproic acid (HICA). Its full name is DL-alpha-hydroxy-isocaproic acid. [Structural formula on the right.] It’s found in muscles and tendons when cells burn the amino acid leucine.

Muscle cells are always on the lookout for leucine. If they find many leucine molecules they conclude that there's a lot of amino acid present and start to produce more muscle protein. A leucine metabolite like HICA tells muscle cells that they are burning amino acids, and that they need to step up their anti-catabolic processes.

Another leucine metabolite you’re probably familiar with is HMB. HMB inhibits the entire protein metabolism process in muscle cells, and is sold as an anticatabolic supplement.

The Finns came across HICA when they found a patent filed by researchers at the American Johns Hopkins University in 1973. According to this, oxidised amino acids inhibit the breakdown of proteins in the body. [US Patent 1444621] The researchers, sports scientists at Finnish universities, bought the metabolite from a bulk supplier and gave it to soccer players, wrestlers and basketball players. When they got positive results, they immediately filed for a patent on the use of the amino acids in sports supplements. [US Patent 20080108698]

From the patent research we compiled the table below. It shows the effect of a 6-week course of HICA on a basketball player who took half a gram of HICA three times a day.

che ne pensate?? conoscevate questa molecola??

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mistersalvo All the Truth Member Messaggi: 2,207 Data registrazione: Jan 2008	HMB’s successor is called HICA - 03-07-2010, 01:03 PM HMB’s successor is called HICA here are already supplements that contain HICA on the market, but they contain too little of the amino acid to be effective. Now everyone’s waiting for the product from Oy Elmomed, the company that the inventors of HICA set up; or someone who doesn’t take patent law so seriously and decides to market the leucine metabolite themselves. According to a human study published in the Journal of the International Society of Sports Nutrition, the substance is anabolic. The compound we’re talking about is called L-leucic acid, but the Finns call it alpha-hydroxy-isocaproic acid (HICA). Its full name is DL-alpha-hydroxy-isocaproic acid. [Structural formula on the right.] It’s found in muscles and tendons when cells burn the amino acid leucine. Muscle cells are always on the lookout for leucine. If they find many leucine molecules they conclude that there's a lot of amino acid present and start to produce more muscle protein. A leucine metabolite like HICA tells muscle cells that they are burning amino acids, and that they need to step up their anti-catabolic processes. Another leucine metabolite you’re probably familiar with is HMB. HMB inhibits the entire protein metabolism process in muscle cells, and is sold as an anticatabolic supplement. The Finns came across HICA when they found a patent filed by researchers at the American Johns Hopkins University in 1973. According to this, oxidised amino acids inhibit the breakdown of proteins in the body. [US Patent 1444621] The researchers, sports scientists at Finnish universities, bought the metabolite from a bulk supplier and gave it to soccer players, wrestlers and basketball players. When they got positive results, they immediately filed for a patent on the use of the amino acids in sports supplements. [US Patent 20080108698] From the patent research we compiled the table below. It shows the effect of a 6-week course of HICA on a basketball player who took half a gram of HICA three times a day. che ne pensate?? conoscevate questa molecola??